Posted in: Uncategorized

Zhanglab 组会安排 -2023年

时间小组记录人汇报人
2023.3.8刘雪婷丛展任局逸
2023.3.15王为善吕康杰李川
2023.3.22王申林邢翠平李晓娴
2023.3.29谭高翼陈海红王枢刘
2023.4.5周立铭
2023.4.12夏雪奎梁敏东
2023.4.19刘雪婷张维燕
2023.4.26张敬宇王枢刘
2023.5.3王为善曾晓倩杨博文
2023.5.10王为善蒋悦杨志恒
2023.5.17王申林局屹
2023.5.24王为善张承昱王正锋
2023.5.31谭高翼喻俊杰
2023.6.7王为善叶可侯英睿
2023.6.13夏雪奎郑立芬
2023.6.20王为善杨博文张承昱
2023.6.27张敬宇王正铎

Posted in: Publication

Year 2023

  1. Lian Wu, Zhanfeng Wang, Yixin Cen, Binju Wang, Jiahai Zhou (2022) Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1, Angewandte Chemie - International Edition 61(12), John Wiley and Sons Inc,

  2. Lan Jiang, Tianji Zhang, Hongzhong Lu, Saijuan Li, Kangjie Lv, Alex Tuffour, Lixin Zhang, Kan Ding, Jin-Ping Li, Hongmei Li, Xueting Liu (2023) Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing, Synthetic and Systems Biotechnology 8(1), p. 11-19,

  3. Yuting Shuai, Yi Ju, Yuanhang Li, Dini Ma, Lan Jiang, Jingyu Zhang, Gao-Yi Tan, Xueting Liu, Shenlin Wang, Lixin Zhang, Guang Liu (2023) A rapid nucleic acid detection platform based on phosphorothioate-DNA and sulfur binding domain, Synthetic and Systems Biotechnology 8(2), p. 213-219,

  4. Yaojun Tong, Lixin Zhang (2023) Discovering the next decade's synthetic biology research trends with ChatGPT, Synthetic and Systems Biotechnology 8(2), p. 220-223, KeAi Communications Co.,

  5. Lan Jiang, Tianji Zhang, Hongzhong Lu, Saijuan Li, Kangjie Lv, Alex Tuffour, Lixin Zhang, Kan Ding, Jin Ping Li, Hongmei Li, Xueting Liu (2023) Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing, Synthetic and Systems Biotechnology 8(1), p. 11-19, KeAi Communications Co.,

  6. Mengzhen Jiang, Man Liu, Guodi Liu, Jiawen Ma, Lixin Zhang, Shenlin Wang (2023) Advances in the structural characterization of complexes of therapeutic antibodies with PD-1 or PD-L1, mAbs 15(1), p. 2236740, NLM (Medline),

  7. Jiaming Yu, Dongyuan Lv, Lixin Zhang (2023) De novo biosynthesis of a vinblastine precursor in Pichia pastoris, Synthetic and Systems Biotechnology 8(2), p. 300-301, KeAi Communications Co.,

  8. Xiaoqian Zeng, Shuliu Wang, Mindong Liang, Weishan Wang, Yue Jiang, Fei Xu, Leshi Liu, Hao Yan, Yaojun Tong, Lixin Zhang, Gao Yi Tan (2023) An in vitro CRISPR-Cas12a-mediated protocol for direct cloning of large DNA fragments, STAR Protocols 4(3), Cell Press,

  9. Yijie Shen, Guodi Liu, Qian Zhang, Xiaoli Tian, Liming Ouyang, Lixin Zhang (2023) Construction of CAR-T cells targeting TM4SF1 and its anti-tumor capacity in ovarian cancer, Immunology Letters 255, p. 1-9, Elsevier B.V.,

  10. Yuting Shuai, Yi Ju, Yuanhang Li, Dini Ma, Lan Jiang, Jingyu Zhang, Gao Yi Tan, Xueting Liu, Shenlin Wang, Lixin Zhang, Guang Liu (2023) A rapid nucleic acid detection platform based on phosphorothioate-DNA and sulfur binding domain, Synthetic and Systems Biotechnology 8(2), p. 213-219, KeAi Communications Co.,

  11. Yuting Shuai, Anan Xu, Jiayi Li, Zhaoxi Han, Dini Ma, Hairong Duan, Xinye Wang, Lan Jiang, Jingyu Zhang, Gao Yi Tan, Xueting Liu, Yi Lei Zhao, Yaojun Tong, Shenlin Wang, Xinyi He, Zixin Deng, Guang Liu, Lixin Zhang (2023) Profile and relaxation of sequence-specificity of DNA sulfur binding domains facilitate new nucleic acid detection platform, Science Bulletin, Elsevier B.V.,

  12. Wenming Yang, Tao Yuan, Zhaolun Cai, Qin Ma, Xueting Liu, Hang Zhou, Siyuan Qiu, Lie Yang (2023) Laparoscopic versus ultrasound-guided transversus abdominis plane block for postoperative pain management in minimally invasive colorectal surgery: a meta-analysis protocol, Frontiers in Oncology 13, Frontiers Media S.A.,

  13. Sishi Lin, Ji Zhang, Bo Chen, Duo Li, Yan Liang, Ya Hu, Xueting Liu, Yongheng Bai, Chaosheng Chen (2023) Role of crescents for lupus nephritis in clinical, pathological and prognosis: a single-center retrospective cohort study, European Journal of Medical Research 28(1), BioMed Central Ltd,

  14. Mengmeng Wang, Kunyu Qu, Peipei Zhao, Xin Yin, Yiwei Meng, Piet Herdewijn, Chao Liu, Lixin Zhang, Xuekui Xia (2023) Synthesis and anticancer evaluation of acetylated-lysine conjugated gemcitabine prodrugs, RSC Medicinal Chemistry 14(8), p. 1572-1580, Royal Society of Chemistry,

  15. Zhaojuan Zheng, Xia Wang, Liming Ouyang, Wenxia Chen, Lixin Zhang, Yulin Cao (2023) Antioxidants Improve the Proliferation and Efficacy of hUC-MSCs against H2O2-Induced Senescence, Antioxidants 12(7), Multidisciplinary Digital Publishing Institute (MDPI),

  16. Tao Zhang, Jianjv Feng, Wenni He, Xiaoting Rong, Hui Lv, Jun Li, Xinxin Li, Hao Wang, Lu Wang, Lixin Zhang, Liyan Yu (2023) Genomic and Transcriptomic Approaches Provide a Predictive Framework for Sesquiterpenes Biosynthesis in Desarmillaria tabescens CPCC 401429, Journal of Fungi 9(4), MDPI,

  17. Meijun Shi, Mingfu Gao, Hao Sun, Weichao Yang, Hongxia Zhao, Lixin Zhang, Hui Xu (2023) Exogenous 2-keto-L-gulonic Acid Supplementation as a Novel Approach to Enhancing L-ascorbic Acid Biosynthesis in Zebrafish (Danio rerio), Animals 13(15), Multidisciplinary Digital Publishing Institute (MDPI),

  18. Jiaming Yu, Dongyuan Lv, Lixin Zhang (2023) De novo biosynthesis of a vinblastine precursor in Pichia pastoris, Synthetic and Systems Biotechnology 8(2), p. 300-301, KeAi Communications Co.,

  19. Haishuo Ji, Lei Wan, Yanxin Gao, Ping Du, Wenjin Li, Hang Luo, Jiarui Ning, Yingying Zhao, Huangwei Wang, Lixin Zhang, Liyun Zhang (2023) Hydrogenase as the basis for green hydrogen production and utilization, Journal of Energy Chemistry 85, p. 348-362, Elsevier B.V.,

  20. Zhiheng Yang, Zilong Li, Bixiao Li, Ruihong Bu, Gao Yi Tan, Zhengduo Wang, Hao Yan, Zhenguo Xin, Guojian Zhang, Ming Li, Hua Xiang, Lixin Zhang, Weishan Wang (2023) A thermostable type I-B CRISPR-Cas system for orthogonal and multiplexed genetic engineering, Nature Communications 14(1), Nature Research,

  21. Wenyue Hu, Bingxu Yang, Qingjie Xiao, Yuli Wang, Yuting Shuai, Gong Zhao, Lixin Zhang, Zixin Deng, Xinyi He, Guang Liu (2023) Characterization of a promiscuous DNA sulfur binding domain and application in site-directed RNA base editing, Nucleic Acids Research 51(19), p. 10782-10794, Oxford University Press,

  22. Xinye Wang, Sha Hu, Jun Wang, Tao Zhang, Ke Ye, Aiwen Wen, Guoliang Zhu, Arturo Vegas, Lixin Zhang, Wupeng Yan, Xueting Liu, Pinghua Liu (2023) Biochemical and Structural Characterization of OvoATh2: A Mononuclear Nonheme Iron Enzyme from Hydrogenimonas thermophila for Ovothiol Biosynthesis, ACS Catalysis 13(23), p. 15417-15426, American Chemical Society,

Posted in: Publication

Year 2022

  1. Zhenghong Li, Chengyu Zhang, Zhengduo Wang, Hao Yan, Chuan Li, Zhiheng Yang, Zilong Li, Lixin Zhang, Weishan Wang (2022) High-throughput and reliable acquisition of in vivo turnover number fuels precise metabolic engineering, Synthetic and Systems Biotechnology 7(1), p. 541-543,

  2. Mostafa Basiony, Liming Ouyang, Danni Wang, Jiaming Yu, Liming Zhou, Mohan Zhu, Xuyuan Wang, Jie Feng, Jing Dai, Yijie Shen, Chengguo Zhang, Qiang Hua, Xiuliang Yang, Lixin Zhang (2022) Optimization of microbial cell factories for astaxanthin production: Biosynthesis and regulations, engineering strategies and fermentation optimization strategies, Synthetic and Systems Biotechnology 7(2), p. 689-704,

  3. Ronghai Cheng, Andrew C. Weitz, Jared Paris, Yijie Tang, Jingyu Zhang, Heng Song, Nathchar Naowarojna, Kelin Li, Lu Qiao, Juan Lopez, Mark W. Grinstaff, Lixin Zhang, Yisong Guo, Sean Elliott, Pinghua Liu (2022) OvoA Mtht from Methyloversatilis thermotolerans ovothiol biosynthesis is a bifunction enzyme: thiol oxygenase and sulfoxide synthase activities, Chemical Science 13(12), p. 3589-3598,

  4. Xiangyin Chen, Jiaming Yu, Lixin Zhang (2022) Enhancing methanol biotransformation for overproducing fatty acid derivatives, Synthetic and Systems Biotechnology 7(4), p. 1187-1188, url,

  5. Guoliang Zhu, Wupeng Yan, Xinye Wang, Ronghai Cheng, Nathchar Naowarojna, Kun Wang, Jun Wang, Heng Song, Yuyang Wang, Hairong Liu, Xuekui Xia, Catherine E. Costello, Xueting Liu, Lixin Zhang, Pinghua Liu (2022) Dissecting the Mechanism of the Nonheme Iron Endoperoxidase FtmOx1 Using Substrate Analogues, JACS Au 2(7), p. 1686-1698, url,

  6. Mindong Liang, Leshi Liu, Fei Xu, Xiaoqian Zeng, Ruijun Wang, Jinling Yang, Weishan Wang, Loganathan Karthik, Jiakun Liu, Zhiheng Yang, Guoliang Zhu, Shuliu Wang, Linquan Bai, Yaojun Tong, Xueting Liu, Min Wu, Li-Xin Zhang, Gao-Yi Tan (2022) Activating cryptic biosynthetic gene cluster through a CRISPR–Cas12a-mediated direct cloning approach, Nucleic Acids Research 50(6), p. 3581-3592,

  7. Xiaoli Zhao, Xiaomin Ma, John H. Dupius, Ruxi Qi, Jenny Tian, Jiaxin Chen, Xiuyuan Ou, Zhaohui Qian, Dehai Liang, Peiyi Wang, Rickey Y. Yada, Shenlin Wang (2022) Negatively charged phospholipids accelerate the membrane fusion activity of the plant-specific insert domain of an aspartic protease, Journal of Biological Chemistry 298(1),

  8. Sha Zhao, Xinming Li, Ziyang Wen, Mengbing Zou, Ge Yu, Xiangyang Liu, Jiafei Mao, Lixin Zhang, Yi Xue, Riqiang Fu, Shenlin Wang (2022) Dynamics of base pairs with low stability in RNA by solid-state nuclear magnetic resonance exchange spectroscopy, iScience 25(11), p. 105322,

  9. Mostafa Basiony, Liming Ouyang, Danni Wang, Jiaming Yu, Liming Zhou, Mohan Zhu, Xuyuan Wang, Jie Feng, Jing Dai, Yijie Shen, Chengguo Zhang, Qiang Hua, Xiuliang Yang, Lixin Zhang (2022) Optimization of microbial cell factories for astaxanthin production: Biosynthesis and regulations, engineering strategies and fermentation optimization strategies, Synthetic and Systems Biotechnology 7(2),

  10. Lan Jiang, Kangjie Lv, Guoliang Zhu, Zhi Lin, Xue Zhang, Cuiping Xing, Huanting Yang, Weiyan Zhang, Zhixin Wang, Chengwei Liu, Xudong Qu, Tom Hsiang, Lixin Zhang, Xueting Liu (2022) Norditerpenoids biosynthesized by variediene synthase-associated P450 machinery along with modifications by the host cell Aspergillus oryzae, Synthetic and Systems Biotechnology 7(4), p. 1142-1147,

  11. Lan Jiang, Huanting Yang, Xue Zhang, Xiaoying Li, Kangjie Lv, Weiyan Zhang, Guoliang Zhu, Chengwei Liu, Yongheng Wang, Tom Hsiang, Lixin Zhang, Xueting Liu (2022) Schultriene and nigtetraene: two sesterterpenes characterized from pathogenetic fungi via genome mining approach, Applied Microbiology and Biotechnology 106(18), p. 6047-6057,

  12. Dan-Ni Wang, Jie Feng, Chen-Xi Yu, Xin-Kai Zhang, Jun Chen, Liu-Jing Wei, Zhijie Liu, Liming Ouyang, Lixin Zhang, Qiang Hua, Feng Liu (2022) Integrated pathway engineering and transcriptome analysis for improved astaxanthin biosynthesis in Yarrowia lipolytica, Synthetic and Systems Biotechnology 7(4), p. 1133-1141,

  13. Xuyuan Wang, Mersa Darbandsari, Lixin Zhang, Zixin Deng (2022) Exploiting synthetic regulatory elements for non-dominant microorganisms, Synthetic and Systems Biotechnology 7(2), p. 839-840,

  14. Xinye Wang, Zhixin Wang, Guoliang Zhu, Lan Jiang, Weiyan Zhang, Yiyi Huang, Zhanren Cong, Yi-Lei Zhao, Jian-He Xu, Tom Hsiang, Lixin Zhang, Qi Chen, Xueting Liu (2022) Chemical control over the conversion between bicyclic and polycyclic terpenes by fungal bifunctional terpene synthases, Chemical Communications 58(68), p. 9476-9479,

Posted in: Publication

Year 2021

  1. Zhiheng Yang, Qingqing Sun, Gaoyi Tan, Quanwei Zhang, Zhengduo Wang, Chuan Li, Fengxian Qi, Weishan Wang, Lixin Zhang, Zilong Li (2021) Engineering thermophilic Geobacillus thermoglucosidasius for riboflavin production, Microbial Biotechnology 14(2), p. 363-373, pubmed,

  2. Yaojun Tong, Jingyu Zhang, Nuo Sun, Xiang Ming Wang, Qi Wei, Yu Zhang, Ren Huang, Yingying Pu, Huanqin Dai, Biao Ren, Gang Pei, Fuhang Song, Guoliang Zhu, Xinye Wang, Xuekui Xia, Xiangyin Chen, Lan Jiang, Shenlin Wang, Liming Ouyang, Ning Xie, Buchang Zhang, Yuanying Jiang, Xueting Liu, Richard Calderone, Fan Bai, Lixin Zhang, Gil Alterovitz (2021) Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p, Science Bulletin 66(18), p. 1895-1905,

  3. Jingyu Zhang, Lan Jiang, Xiangyin Chen, Kangjie Lv, Mostafa Basiony, Guoliang Zhu, Loganathan Karthik, Liming Ouyang, Lixin Zhang, Xueting Liu (2021) Recent advances in biotechnology for marine enzymes and molecules, Current Opinion in Biotechnology 69, p. 308-315,

  4. Lan Jiang, Pei Huang, Biao Ren, Zhijun Song, Guoliang Zhu, Wenni He, Jingyu Zhang, Ayokunmi Oyeleye, Huanqin Dai, Lixin Zhang, Xueting Liu (2021) Antibacterial polyene-polyol macrolides and cyclic peptides from the marine-derived Streptomyces sp. MS110128, Applied Microbiology and Biotechnology 105(12), p. 4975-4986,

  5. Xiangxiang Zhao, Shanshan Li, Guang Liu, Zhong Wang, Zhiheng Yang, Quanwei Zhang, Mindong Liang, Jiakun Liu, Zilong Li, Yaojun Tong, Guoliang Zhu, Xinye Wang, Lan Jiang, Weishan Wang, Gao Yi Tan, Lixin Zhang (2021) A versatile biosensing platform coupling CRISPR–Cas12a and aptamers for detection of diverse analytes, Science Bulletin 66(1), p. 69-77,

  6. Lan Jiang, Guoliang Zhu, Jianying Han, Chengjian Hou, Xue Zhang, Zhixin Wang, Weize Yuan, Kangjie Lv, Zhanren Cong, Xinye Wang, Xiangyin Chen, Loganathan Karthik, Huanting Yang, Xuyuan Wang, Gaoyi Tan, Guang Liu, Liya Zhao, Xuekui Xia, Xiangyang Liu, Shushan Gao, Lei Ma, Mei Liu, Biao Ren, Huanqin Dai, Ronald J. Quinn, Tom Hsiang, Jingyu Zhang, Lixin Zhang, Xueting Liu (2021) Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi, Applied Microbiology and Biotechnology 105(13), p. 5407-5417,

  7. Lan Jiang, Xue Zhang, Yuya Sato, Guoliang Zhu, Atsushi Minami, Weiyan Zhang, Taro Ozaki, Bin Zhu, Zhixin Wang, Xinye Wang, Kangjie Lv, Jingyu Zhang, Yongheng Wang, Shushan Gao, Chengwei Liu, Tom Hsiang, Lixin Zhang, Hideaki Oikawa, Xueting Liu (2021) Genome-Based Discovery of Enantiomeric Pentacyclic Sesterterpenes Catalyzed by Fungal Bifunctional Terpene Synthases, Organic Letters 23(12), p. 4645-4650,

  8. Jiong Zhang, Xiangxiang Zhaob, John R. Cappiello, Yi Yang, Yunfei Cheng, Guang Liu, Wenjing Fang, Yinzhu Luo, Yu Zhang, Jiajia Dong, Lixin Zhang, K. Barry Sharpless (2021) Identification of simple arylfluorosulfates as potent agents against resistant bacteria, Proceedings of the National Academy of Sciences of the United States of America 118(28),

  9. Guoxing Xu, Qi Wei, Fuhang Song, Huanqin Dai, Lihua Deng, Xiaoping Zhou, Lixin Zhang, Qun Dang, Xu Bai (2021) Design and Synthesis of Aza-β-Carboline Analogs and their Antibacterial Evaluation, Pharmaceutical Chemistry Journal 55, p. 365-372,

  10. Yaojun Tong, Jingyu Zhang, Nuo Sun, Xiang Ming Wang, Qi Wei, Yu Zhang, Ren Huang, Yingying Pu, Huanqin Dai, Biao Ren, Gang Pei, Fuhang Song, Guoliang Zhu, Xinye Wang, Xuekui Xia, Xiangyin Chen, Lan Jiang, Shenlin Wang, Liming Ouyang, Ning Xie, Buchang Zhang, Yuanying Jiang, Xueting Liu, Richard Calderone, Fan Bai, Lixin Zhang, Gil Alterovitz (2021) Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p, Science Bulletin,

  11. Caixia Chen, Xiangyin Chen, Biao Ren, Hui Guo, Wael M Abdel-Mageed, Xueting Liu, Fuhang Song, Lixin Zhang (2021) Characterization of Streptomyces sp. LS462 with high productivity of echinomycin, a potent antituberculosis and synergistic antifungal antibiotic, Journal of Industrial Microbiology and Biotechnology 48(9-10), p. kuab079,

  12. Peipei Zhao, Meng Yang, Guoliang Zhu, Bo Zhao, Hong Wang, Hairong Liu, Xinzhu Wang, Jun Qi, Xin Yin, Lumin Yu, Yiwei Meng, Zhipu Li, Lixin Zhang, Xuekui Xia (2021) Mollicellins S-U, three new depsidones from Chaetomium brasiliense SD-596 with anti-MRSA activities, Journal of Antibiotics 74, p. 317-323,

  13. Jianying Han, Lan Jiang, Lixin Zhang, Ronald J. Quinn, Xueting Liu, Yunjiang Feng (2021) Peculiarities of meroterpenoids and their bioproduction, Applied Microbiology and Biotechnology 105, p. 3987-4003,

  14. Shanshan Li, Bowen Yang, Gao Yi Tan, Li Ming Ouyang, Shiwen Qiu, Weishan Wang, Wensheng Xiang, Lixin Zhang (2021) Polyketide pesticides from actinomycetes, Current Opinion in Biotechnology 69, p. 299-307,

  15. Panpan Wu, Ketao Chen, Bowen Li, Yanni Zhang, Hang Wu, Yuhong Chen, Shaohua Ren, Sabir Khan, Lixin Zhang, Buchang Zhang (2021) Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes, mBio 12(5),

  16. Xiangxiang Zhao, Zhengduo Wang, Bowen Yang, Zilong Li, Yaojun Tong, Yuhai Bi, Zhenghong Li, Xuekui Xia, Xiangyin Chen, Lixin Zhang, Weishan Wang, Gao Yi Tan (2021) Integrating PCR-free amplification and synergistic sensing for ultrasensitive and rapid CRISPR/Cas12a-based SARS-CoV-2 antigen detection, Synthetic and Systems Biotechnology 6(4), p. 283-291,

  17. Wanying Lu, Guoliang Zhu, Weize Yuan, Zhaoxi Han, Huanqin Dai, Mostafa Basiony, Lixin Zhang, Xueting Liu, Tom Hsiang, Jingyu Zhang (2021) Two novel aliphatic unsaturated alcohols isolated from a pathogenic fungus Fusarium proliferatum, Synthetic and Systems Biotechnology 6(4), p. 446-451,

  18. Insung Na, Huanqin Dai, Hantian Li, Anvita Gupta, David Kreda, Powell Zhang, Xiangyin Chen, Lixin Zhang, Gil Alterovitz (2021) Computational prediction and validation of specific EmbR binding site on PknH, Synthetic and Systems Biotechnology 6(4), p. 429-436,

  19. Yaojun Tong, Jingyu Zhang, Luoqiang Wang, Qinqin Wang, Huang Huang, Xiangyin Chen, Qing Zhang, Hantian Li, Nuo Sun, Guang Liu, Buchang Zhang, Fuhang Song, Gil Alterovitz, Huanqin Dai, Lixin Zhang (2021) Hyper-Synergistic Antifungal Activity of Rapamycin and Peptide-Like Compounds against Candida albicans Orthogonally via Tor1 Kinase, ACS Infectious Diseases 7(10), p. 2826-2835,

Posted in: Uncategorized

小朋友们一起上网课

The only true wisdom is in knowing you know nothing.

Socrates

期末大作业

  • 复习一下之前的xmind的笔记,选择一个你喜欢的章节。
  • 在一张白纸上手绘思维导图,向你的父母/朋友/同学讲解一下。
  • 请他们提几个问题,简要记录下问题和你的回答。

7月25日

  • 学习第9章的内容。
  • 请私信我:
    • 除了课程视频中介绍的Perl之外,你之前还学习过哪些编程语言呢?
    • 完上面的内容花了多少时间(听课花了多少时间,整理成xmind用了多少时间)?
  • 以下部分不做强制要求。
  • Linux 系统基本操作。
    • 如果是windows 10操作系统的电脑,可以尝试一下这个
    • 其中“所选的 Linux 分发版”:请选择Ubuntu
    • 如果是Mac操作系统的电脑,可以直接在命令行中输入Linux的命令。
  • 安装perl,并动手试试吧。之前没有编程基础的同学,请从R语言或者Python开始学习。
  • 对网页设计有兴趣的小朋友,请私信我。

7月24日

  • 学习第8章的内容。
  • 完上面的内容花了多少时间(听课花了多少时间,整理成xmind用了多少时间)?请私信我。
  • 请下载weka,并尝试一下练习题。如果在安装软件的过程遇到了困难,请私信我吧。

7月23日

  • 学习第6,7章的内容
  • 完上面的内容花了多少时间(听课花了多少时间,整理成xmind用了多少时间)?请私信我。

7月22日

  • 学习第5章的内容
  • 完上面的内容花了多少时间(听课花了多少时间,整理成xmind用了多少时间)?请私信我。

7月21日

  • 学习第4章的内容
  • 预习第5章(第一部分)
  • 完上面的内容花了多少时间(听课花了多少时间,整理成xmind用了多少时间)?请私信我。
  • 文件名请使用,你的名字_文件名_数字

7月20日

  • 同7月18日。

7月18日

  • 请大家下载免费软件xmind
  • 学习第1,2章的内容
  • 试着用xmind记录你的思路
    • 文件名请使用,你的名字_文件名_数字。
    • 把文件保存并上传到腾讯微云
    • 把文件分享到我们的群里。
  • 完上面的内容花了多少时间(听课花了多少时间,整理成xmind用了多少时间)?请私信我。

期末大作业2

  • 新型冠状病毒肆虐全球,而我们对它的了解还很少。
  • 试着运用之前所学到的生物信息学的知识,对新型冠状病毒的序列数据做一点分析:
    • 关于新型冠状病毒,有哪些问题是你想要知道的呢?
    • 构建一个反映新型冠状病毒和其他病毒序列之间亲缘关系的系统发育树(Phylogenetic tree),并美化它。
    • 之前所学过的哪些章节,可以对解决你提出的这个问题有帮助呢?
    • 整理一个研究思路,并在xmind文件中记录下来。

Posted in: Publication_new

2016_backup

  1. Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, Boya P CA, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O’Neill EC, Briand E, Helfrich EJ, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AM, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang LX, Knight R, Jensen PR, Palsson BØ, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N. 2016. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 9;34(8):828-837. doi: 10.1038/nbt.3597.
  2. Li S, Zhou L, Yao Y, Fan K, Li Z, Zhang LX, Wang W, Yang K. 2016. A platform for the development of novel biosensors by configuring allosteric transcription factor recognition with amplified luminescent proximity homogeneous assays. Chem Commun (Camb) 53(1):99-102.
  3. Tong Y, Liu M, Zhang Y, Liu X, Huang R, Song F, Dai H, Ren B, Sun N, Pei G, Bian J, Jia XM, Huang G, Zhou X, Li S, Zhang B, Fukuda T, Tomoda H, Ōmura S, Cannon RD, Calderone R, Zhang LX*. Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters. Synth Syst Biotechnol. 2016. 1(3):158-168
  4. Abdel-Mageed WM, et al. Mei Liu, Jingyu Zhang, Zhang LX*, Xueting Liu*. 2016. Non- Cyanogenic Cyanoglucoside Cyclooxygenase Inhibitors from Simmondsiachinensis. Organic Letters, 15;18(8):1728-31. doi: 10.1021/acs.orglett.6b00206.
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